A tech question

Please excuse a commercial moment, if you will, but since the writers here are obviously heavy users of writing-related technologies, any thoughts on the the default OpenOffice Writer/Microsoft Word button layout for use with a forthcoming high-tech mouse would be appreciated. The top two segments show the 16 buttons (with clicks and double-clicks) on the top of the device, the bottom row shows a) the joystick click and the side button, b) the scroll wheel (up, click/double-click, and down), and c) the four joystick positions (plus the four yellow positions when the joystick is pressed in).

Any thoughts and suggestions for potential improvement would be most helpful. This is for a broad-spectrum default mode, an extreme range of customization including macros is permitted but not desired for the defaults. Thank you.